27 Aralık 2016 Salı

Psoriasis


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Vitiligo Animal Friends



Transmission or Cause: Vitiligo is a hereditary disorder of skin and/or hair pigment loss, and is caused by immune-mediated destruction of the pigment producing cells in the skin.

 Affected Animals: Although any animal or breed can be affected, vitiligo has an increased incidence in Rottweilers, Doberman pinschers, Belgian Tervurens and Siamese cats.

 Clinical signs: Symptoms usually begin in young adulthood. Patchy areas of pigment loss may involve the skin, hair or both. Most commonly affected areas include lips, nose, eyelids, face and footpads. There is no associated itching, inflammation, rash, skin ulcers, or crusts.

 Diagnosis: Careful examination of clinical signs and skin biopsy to rule out other more serious causes of pigment loss such as lupus, uveodermatologic syndrome, or skin cancer are necessary. Skin biopsy shows loss of pigment and pigment-producing skin cells, but minimal to no inflammation or other abnormalities.

 Treatment: There is no effective treatment for vitiligo in companion animals. In humans, treatment options include topical immunosuppressive medications or ultraviolet phototherapy, but therapy often causes only partial improvement.

 Prognosis: Although the prognosis for regaining normal skin pigmentation is poor, in animals vitiligo is only a cosmetic disorder, with no effect on quality of life. In some animals, spontaneous repigmentation may occur.
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Koebner Phenomenon


The Koebner phenomenon or Köbner phenomenon also called the Koebner response or the isomorphic response, attributed to Heinrich Köbner, is the appearance of skin lesions on lines of trauma.[2] The Koebner phenomenon may result from either a linear exposure or irritation. Conditions demonstrating linear lesions after a linear exposure to a causative agent include: molluscum contagiosum, warts and toxicodendron dermatitis (a dermatitiscaused by a genus of plants including poison ivy). Warts and molluscum contagiosum lesions can be spread in linear patterns by self-scratching ("auto-inoculation"). Toxicodendron dermatitis lesions are often linear from brushing up against the plant. Causes of the Koebner phenomenon that are secondary to scratching rather than an infective or chemical cause include vitiligo, psoriasis, lichen planus, lichen nitidus, pityriasis rubra pilaris, and keratosis follicularis (Darier disease).
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20 Aralık 2016 Salı

Leakage gut


"Leaky gut syndrome" is a proposed condition some health practitioners claim is the cause of a wide range of long-term conditions, including chronic fatigue syndrome and multiple sclerosis (MS).
Proponents of "leaky gut syndrome" claim that many symptoms and conditions are caused by the immune system reacting to germs, toxins or other substances that have been absorbed into the bloodstream via a porous ("leaky") bowel.
While it's true that some conditions and medications can cause a "leaky" gut (what scientists call increased intestinal permeability), there is currently little evidence to support the theory that a porous bowel is the direct cause of any significant, widespread problems.
There is also little evidence that the "treatments" some people claim help to reduce bowel leakiness, such as nutritional supplements and herbal remedies, have any beneficial effect for most of the conditions they supposedly help.

What can cause a "leaky" bowel?

The inside of the bowel is lined by a single layer of cells that make up the mucosal barrier (the barrier between the inside of the gut and the rest of the body).
This barrier is effective at absorbing nutrients, but prevents most large molecules and germs passing from inside the bowel into the bloodstream and potentially causing widespread symptoms.
In some circumstances, this barrier can become less effective and "leaky", although this in itself is not generally thought to be sufficient to cause serious problems.

Alcohol and certain painkillers

Alcohol, aspirin and non-steroidal anti-inflammatory drugs (NSAIDs)such as ibuprofen are well-known irritants of the bowel lining. They can damage the seals between cells, allowing some substances to pass through the gaps and into the bloodstream.
Gastroenterologists (specialists in gut conditions) generally agree that these irritants don't usually cause anything more than just mild inflammation of a particular area of the bowel.
This will usually cause no obvious symptoms and will improve over time if you stop taking the medication or stop drinking alcohol. At the very worst, the inflammation might be bad enough to occasionally cause ulcers in the bowel lining.

Certain conditions and treatments

The following conditions and treatments can also damage the seals in the bowel lining:
Generally, even in these situations treatment for a "leaky" bowel isn’t necessary. However, under certain circumstances people with Crohn's disease, for example, may benefit from a liquid diet to reduce bowel inflammation, which also improves the leaky bowel (read more about treating Crohn's disease).

The "leaky gut syndrome" theory

Exponents of "leaky gut syndrome" – largely practitioners of complementary and alternative medicine – believe the bowel lining can become irritated and leaky as the result of a much wider range of factors, including an overgrowth of yeast or bacteria in the bowel, a poor diet and the overuse of antibiotics.
They believe that undigested food particles, bacterial toxins and germs can pass through the "leaky" gut wall and into the bloodstream, triggering the immune system and causing persistent inflammation throughout the body. This, they say, is linked to a much wider range of health problems, including:
However, there is currently little evidence to suggest these conditions are in fact caused by having a leaky gut.

Promoted products

Many different "treatments" have been suggested by people who promote the idea of leaky gut syndrome, including diet books, nutritional supplements (containing probiotics, for example), herbal remedies, gluten-free foods and other special diets, such as a low FODMAP, low sugar or antifungal diet.
However, you should be wary of treatments offered by people who claim to be able to "cure leaky gut syndrome", as there is little scientific evidence to suggest they are beneficial for many of the conditions they are claimed to help.
Some of the dietary changes suggested for "leaky gut syndrome" (such as a low FODMAP diet) can help people with irritable bowel syndrome (IBS), but these seem to work irrespective of the presence of a "leaky" gut.
Generally, eliminating foods from the diet is not a good idea unless it's strictly necessary (for example, if you have coeliac disease) and done on the advice of a healthcare professional, as it can lead to nutritional deficiencies.

Advice and further information

If you have symptoms that are not explained by a diagnosis, it may help to read the topic on medically unexplained symptoms. Such mystery symptoms are surprisingly common, accounting for up to a fifth of all GP consultations in the UK. 
If you have been diagnosed with a particular health condition, you can look it up in our A-Z index of treatments and conditions, where you will find reliable, evidence-based information about its treatment.
Generally, it is wise to view "holistic" and "natural health" websites with scepticism – do not assume that the information they provide is correct or based on scientific facts or evidence.
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3 Aralık 2016 Cumartesi

Black pepper with vitiligo treatment


Vitiligo is a progressive skin disease characterized by loss of skin pigment. The cause is unknown and there is no known effective cure. Current therapies focus on slowing its progression and camouflaging the disorder. However, recent research has shown that an active compound in black pepper may stimulate repigmentation of the skin.

Facts about Vitiligo

Vitiligo is a skin condition in which patches of skin become depigmented due to non-functioning or dead melanocytes, the cells that produce pigment in the skin. The condition is most noticeable in dark skinned people when it occurs on the extremities. The depigmented areas of skin may be small at first but can enlarge and even change shape. There are many different types of vitiligo that are classified by the severity and location of change in pigmentation.

Possible Causes

The causes and progression of vitiligo are poorly understood. Vitiligo is likely an autoimmune disease and there is some research such as in the May 2010 issue of the "New England Journal of Medicine" that suggests it may have a basis in genetic mutations. The March 2007 issue of the "New England Journal of Medicine" reports that other autoimmune diseases may promote the progression of vitiligo such as Addison's disease which affects the adrenal glands. The disease can have severe psychological impact on certain individuals as reported in the journal "Psychotherapy and Psychosomatics."

Effects of Black Pepper

There is no cure for vitiligo but there are several therapies that have shown to have an improvement. One possibly natural treatment for vitiligo is black pepper. Piperine is the substance in black pepper that gives it its heat and many studies have been performed on the role of this compound. One study in the "British Journal of Dermatology" showed that when animals were treated topically with piperine, pigmentation of the skin was increased. Piperine may stimulate inactive melanocytes in the skin leading to pigmentation. For this treatment to be effective, crushed black pepper or its essential oil must be applied to the skin. However its effectiveness in human patients requires further research.

Other Treatments for Vitiligo

Another way to slow the progression of vitiligo is to wear sunscreen and protect the skin from sun exposure. This method is effective for people with light skin to reduce darkening of the unaffected areas of skin. Steroid cream may also be applied to stimulate melanocytes but can have side effects especially in children according to the "Journal of the American Academy of Dermatology". The journal "Pigment Cell and Melanoma Research" describes the use of chemicals such as monobenzone to depigment the unaffected areas of skin but this may take years to accomplish.
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